Large cell neuroendocrine carcinoma (LCNEC) of the urinary bladder: a case report

Diagn Pathol. 2013 Feb 4:8:19. doi: 10.1186/1746-1596-8-19.

Abstract

Neuroendocrine carcinoma of the urinary bladder is a rare entity, accounting less then 1% of urinary bladder malignancies. The vast majority of the neuroendocrine carcinoma of the urinary bladder is represented by small cell neuroendocrine carcinoma while just few cases of large cell neuroendocrine carcinoma (LCNEC) have been reported. In this cases report we describe a rare case of primary bladder LCNEC.

Virtual slides: The virtual slide(s) for this article can be found here: http://www.diagnosticpathology.diagnomx.eu/vs/2474700528951562.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biomarkers, Tumor / analysis
  • Biopsy
  • Carcinoma, Large Cell / chemistry
  • Carcinoma, Large Cell / pathology*
  • Carcinoma, Large Cell / therapy
  • Carcinoma, Neuroendocrine / chemistry
  • Carcinoma, Neuroendocrine / pathology*
  • Carcinoma, Neuroendocrine / therapy
  • Chemotherapy, Adjuvant
  • Cisplatin / administration & dosage
  • Cystectomy
  • Etoposide / administration & dosage
  • Fatal Outcome
  • Female
  • Humans
  • Immunohistochemistry
  • Middle Aged
  • Neoadjuvant Therapy
  • Treatment Outcome
  • Urinary Bladder Neoplasms / chemistry
  • Urinary Bladder Neoplasms / pathology*
  • Urinary Bladder Neoplasms / therapy

Substances

  • Biomarkers, Tumor
  • Etoposide
  • Cisplatin