Abstract
A BODIPY-based fluorescent probe, HCSe, has been successfully developed for the rapid detection of hypochlorous acid based on the specific HOCl-promoted oxidation of diphenyl selenide in response to the amount of HOCl. Confocal fluorescence microscopy imaging using RAW264.7 cells showed that the new probe HCSe could be used as an effective fluorescent probe for detecting HOCl in living cells.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Animals
-
Biphenyl Compounds / chemistry*
-
Boron Compounds / chemical synthesis*
-
Boron Compounds / chemistry
-
Fluorescent Dyes / chemical synthesis*
-
Fluorescent Dyes / chemistry
-
Hypochlorous Acid / analysis*
-
Hypochlorous Acid / chemistry
-
Macrophages / drug effects
-
Mice
-
Molecular Structure
-
Organoselenium Compounds / chemical synthesis*
-
Organoselenium Compounds / chemistry
-
Oxidation-Reduction
Substances
-
4,4-difluoro-4-bora-3a,4a-diaza-s-indacene
-
Biphenyl Compounds
-
Boron Compounds
-
Fluorescent Dyes
-
Organoselenium Compounds
-
diphenyl
-
Hypochlorous Acid