Country-level correlates of cervical cancer mortality in Latin America and the Caribbean

Salud Publica Mex. 2013 Jan-Feb;55(1):5-15. doi: 10.1590/s0036-36342013000100004.

Abstract

Objective: To identify country-level correlates of geographical variations in cervical cancer (CC) mortality in Latin America and the Caribbean (LAC).

Materials and methods: CC mortality rates for LAC countries (n=26) were examined in relation to country-specific socio-economic indicators (n=58) and Human Papilloma Virus (HPV) prevalence using linear regression models.

Results: High mortality at ages <5 years, low per capita total expenditure on health, and low proportion of the population with access to sanitation were identified as the best independent predictors of CC mortality (R² =77%). In the subset of countries (n=10) with HPV prevalence estimates, these socio-economic indicators together with high-risk HPV prevalence explained almost all the between-country variability in CC mortality (R² =98%).

Conclusion: The findings suggest that continuing socioeconomic improvements in LAC countries will be associated with further reductions in CC mortality even in the absence of organised population-based screening and vaccination programmes.

MeSH terms

  • Adolescent
  • Adult
  • Caribbean Region / epidemiology
  • Child
  • Child, Preschool
  • Early Detection of Cancer / statistics & numerical data
  • Female
  • Humans
  • Infant
  • Latin America / epidemiology
  • Middle Aged
  • Papillomavirus Infections / diagnosis
  • Papillomavirus Infections / epidemiology
  • Prevalence
  • Uterine Cervical Neoplasms / diagnosis
  • Uterine Cervical Neoplasms / mortality*
  • Uterine Cervical Neoplasms / virology
  • Young Adult