A physiologically motivated sparse, compact, and smooth (SCS) approach to EEG source localization

Annu Int Conf IEEE Eng Med Biol Soc. 2012:2012:1546-9. doi: 10.1109/EMBC.2012.6346237.

Abstract

Here, we introduce a novel approach to the EEG inverse problem based on the assumption that principal cortical sources of multi-channel EEG recordings may be assumed to be spatially sparse, compact, and smooth (SCS). To enforce these characteristics of solutions to the EEG inverse problem, we propose a correlation-variance model which factors a cortical source space covariance matrix into the multiplication of a pre-given correlation coefficient matrix and the square root of the diagonal variance matrix learned from the data under a Bayesian learning framework. We tested the SCS method using simulated EEG data with various SNR and applied it to a real ECOG data set. We compare the results of SCS to those of an established SBL algorithm.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Bayes Theorem
  • Computer Simulation
  • Electroencephalography / methods*
  • Humans
  • Image Processing, Computer-Assisted / methods*
  • Magnetic Resonance Imaging
  • Models, Theoretical
  • Signal Processing, Computer-Assisted*
  • Signal-To-Noise Ratio