Mood-congruent bias and attention shifts in the different episodes of bipolar disorder

Cogn Emot. 2013;27(6):1114-21. doi: 10.1080/02699931.2013.764281. Epub 2013 Jan 29.

Abstract

An "affective" go/no-go task was used in the different episodes of bipolar patients (euthymic, depressed, and manic) to examine (1) the presence of a mood-congruent attentional bias; and (2) the patients' ability to inhibit and invert associations between stimuli and responses through blocks. A group of healthy individuals served as controls. Results revealed a mood-congruent attentional bias: patients in the manic episode processed positive information faster, whereas those in the depressive episode processed negative information faster. In contrast, neither euthymic patients nor healthy individuals showed any mood-congruent biases. Furthermore, there was a shift cost across blocks for healthy individuals, but not for the patients. This may reflect a general impairment at selecting relevant information (e.g., in terms of disability to inhibit and invert associations between stimuli and responses) in bipolar participants, regardless of their episode. This state/trait dissociation in an episodic and chronic disorder such as bipolar disorder is important for its appropriate characterisation.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Affect*
  • Attention*
  • Bipolar Disorder / psychology*
  • Case-Control Studies
  • Female
  • Humans
  • Inhibition, Psychological
  • Male
  • Middle Aged
  • Psychomotor Performance
  • Reaction Time