Cardiovascular-metabolic impact of adiponectin and aquaporin

Norikazu Maeda; Tohru Funahashi; Iichiro Shimomura

doi:10.1507/endocrj.ej13-0016

Cardiovascular-metabolic impact of adiponectin and aquaporin

Endocr J. 2013;60(3):251-9. doi: 10.1507/endocrj.ej13-0016. Epub 2013 Jan 29.

Authors

Norikazu Maeda¹, Tohru Funahashi, Iichiro Shimomura

Affiliation

¹ Department of Metabolic Medicine, Graduate School of Medicine, Osaka University, Suita 565-0871, Japan. norikazu_maeda@endmet.med.osaka-u.ac.jp

PMID: 23358099
DOI: 10.1507/endocrj.ej13-0016

Abstract

Visceral fat accumulation is located upstream of metabolic syndrome. Recent progress in adipocyte biology has clarified the molecular mechanism for pathophysiology of metabolic syndrome and its related disorders. In this review we summarize adiponectin and aquaporin 7 (AQP7) in the role of metabolic syndrome and cardiovascular diseases.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Adipocytes / physiology
Adiponectin / blood
Adiponectin / genetics
Adiponectin / physiology*
Aquaporins / deficiency
Aquaporins / genetics
Aquaporins / physiology*
Cardiovascular System / physiopathology*
Female
Gene Expression Regulation
Humans
Intra-Abdominal Fat / physiopathology
Male
Metabolic Syndrome / physiopathology*
Obesity

Substances

AQP7 protein, human
AQP9 protein, human
Adiponectin
Aquaporins