CT-guided biopsies in lung infections in patients with haematological malignancies

Diagn Interv Imaging. 2013 Feb;94(2):202-15. doi: 10.1016/j.diii.2012.12.008. Epub 2013 Jan 24.

Abstract

CT-guided transparietal lung biopsy in imaging makes it possible to find the pathogenic agent in half of all fungal infections and most bacterial infections (sensitivity=55%, specificity=100%). Performance is decreased in consolidations (50% of infections) compared to masses. Complications, pneumothorax, alveolar bleeding and hemoptysis are generally benign and rarely (<5%) require specific treatment. On the other hand, the diagnostic performance increases significantly with the calibre of 18G co-axial systems compared to 20G. The risk is not related to the number of samples or platelet levels.

Keywords: Haematological malignancy; Infections; Interventional radiology; Lung biopsy.

Publication types

  • Review

MeSH terms

  • Adult
  • Aged
  • Bacterial Infections / diagnostic imaging*
  • Bacterial Infections / microbiology
  • Bacterial Infections / pathology
  • Hematologic Neoplasms / complications*
  • Humans
  • Image-Guided Biopsy / adverse effects
  • Image-Guided Biopsy / methods*
  • Lung Diseases / diagnostic imaging*
  • Lung Diseases / microbiology
  • Lung Diseases / pathology
  • Lung Diseases, Fungal / diagnostic imaging*
  • Lung Diseases, Fungal / pathology
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / pathology
  • Middle Aged
  • Radiography, Interventional / methods
  • Tomography, X-Ray Computed*