Switches, switches, every where, in any drop we drink

Jérôme Bonnet; Drew Endy

doi:10.1016/j.molcel.2013.01.005

Switches, switches, every where, in any drop we drink

Mol Cell. 2013 Jan 24;49(2):232-3. doi: 10.1016/j.molcel.2013.01.005.

Authors

Jérôme Bonnet¹, Drew Endy

Affiliation

¹ Department of Bioengineering, Y2E2-269B, 473 Via Ortega, Stanford University, Stanford, CA 94305-4201, USA.

PMID: 23352244
DOI: 10.1016/j.molcel.2013.01.005

Abstract

In this issue, Broussard et al. (2013) report genetic switches that regulate cell fate selection; a recombinase attachment site is embedded within a repressor coding sequence, such that integration truncates a proteolysis domain, stabilizing the repressor and setting the switch.

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