A school-based study with Rome III criteria on the prevalence of functional gastrointestinal disorders in Chinese college and university students

PLoS One. 2013;8(1):e54183. doi: 10.1371/journal.pone.0054183. Epub 2013 Jan 18.

Abstract

Background: Functional gastrointestinal disorders, including functional dyspepsia, irritable bowel syndrome and functional constipation are very common worldwide.

Objective: This research aims to estimate the prevalence and associated factors involved in functional gastrointestinal disorders in Chinese college and university students using the Rome III criteria.

Methods: A total of 5000 students from Shandong University in China were asked in January-May 2012 to complete questionnaires, including the Rome III questionnaire, hospital anxiety and depression scale, and negative life events scale.

Results: Based on the 4638 students who completed the questionnaire, the prevalence of functional dyspepsia, irritable bowel syndrome and functional constipation in college and university students of North China worked out to be 9.25%, 8.34% and 5.45% respectively. They were more frequent in female students. The factors of anxiety (OR 1.07; 95% CI 0.99 to 1.16, P=0.002<0.05) and depression (OR 0.55; 95% CI 0.15 to 1.05, P=0.045<0.05) indicated a high risk of causing irritable bowel syndrome.

Conclusion: Functional dyspepsia, irritable bowel syndrome and functional constipation were common in college and university students of North China. Psychological disorders such as anxiety and depression provide significant risk factors for irritable bowel syndrome patients.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anxiety / epidemiology
  • Asian People / statistics & numerical data
  • China / epidemiology
  • Comorbidity
  • Constipation / epidemiology
  • Depression / epidemiology
  • Dyspepsia / epidemiology
  • Female
  • Gastrointestinal Diseases / diagnosis
  • Gastrointestinal Diseases / epidemiology*
  • Gastrointestinal Diseases / psychology
  • Humans
  • Irritable Bowel Syndrome / epidemiology
  • Logistic Models
  • Male
  • Prevalence
  • Risk Assessment / statistics & numerical data
  • Risk Factors
  • Students / psychology
  • Students / statistics & numerical data*
  • Surveys and Questionnaires*
  • Universities*
  • Young Adult

Grants and funding

This study was supported by the Graduate Innovation Foundation of Shandong University (yyx10017). The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.