[Precursors and propeptides of neurotrophic factors as the modulators of biological activity of its mature forms]

L M Rafieva; A V Shubin; E V Gasanov

doi:10.1134/s1068162012050123

[Precursors and propeptides of neurotrophic factors as the modulators of biological activity of its mature forms]

Bioorg Khim. 2012 Sep-Oct;38(5):515-23. doi: 10.1134/s1068162012050123.

[Article in Russian]

Authors

L M Rafieva, A V Shubin, E V Gasanov

PMID: 23342485
DOI: 10.1134/s1068162012050123

Abstract

Here, we review the problems of neurotrophic factors' folding, the role of its precursors (proneurotrophins) and the contribution of elements deleted during its maturation (propeptides) in biological functioning of these growth factors.

Publication types

English Abstract
Research Support, Non-U.S. Gov't
Review

MeSH terms

Animals
Humans
Nerve Growth Factors / physiology*
Protein Folding*
Protein Precursors / physiology*

Substances

Nerve Growth Factors
Protein Precursors