The power of fluorogenic probes

Angew Chem Int Ed Engl. 2013 Feb 25;52(9):2408-10. doi: 10.1002/anie.201209733. Epub 2013 Jan 21.

Abstract

A definite turn-on: Turning on fluorescence only where successful labeling is happening sounds as desirable as delivering a drug only where the drug target resides. New fluorogenic xanthene derivatives from the Bertozzi research group are getting us closer to "magic bullet" dyes.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Fluorescence
  • Fluorescent Dyes / chemistry*
  • Microscopy, Fluorescence / methods*
  • Spectrometry, Fluorescence / methods*

Substances

  • Fluorescent Dyes