Structural effects of proline substitution and metal binding on hexameric cyclic peptoids

Irene Izzo; Graziella Ianniello; Chiara De Cola; Brunello Nardone; Loredana Erra; Gavin Vaughan; Consiglia Tedesco; Francesco De Riccardis

doi:10.1021/ol3034143

Structural effects of proline substitution and metal binding on hexameric cyclic peptoids

Org Lett. 2013 Feb 1;15(3):598-601. doi: 10.1021/ol3034143. Epub 2013 Jan 18.

Authors

Irene Izzo¹, Graziella Ianniello, Chiara De Cola, Brunello Nardone, Loredana Erra, Gavin Vaughan, Consiglia Tedesco, Francesco De Riccardis

Affiliation

¹ Department of Chemistry and Biology, University of Salerno, Via Ponte don Melillo, 84084, Fisciano (SA), Italy. iizzo@unisa.it

PMID: 23330636
DOI: 10.1021/ol3034143

Abstract

L-Proline and N-methoxyethyl glycine have been included in novel cyclic hexameric peptoids. Supramolecular coordination with Na(+) triggered the formation of the first 1D metal-organic framework based on peptoids.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Macrocyclic Compounds / chemistry*
Nuclear Magnetic Resonance, Biomolecular
Peptoids / chemistry*
Proline / chemistry*
Sodium / chemistry*
Stereoisomerism

Substances

Macrocyclic Compounds
Peptoids
Proline
Sodium