Health-care utilization and respiratory morbidities in preterm infants with pulmonary hypertension

J Perinatol. 2013 Jul;33(7):543-7. doi: 10.1038/jp.2012.170. Epub 2013 Jan 17.

Abstract

Objective: To assess health-care utilization and risk of respiratory morbidities in preterm infants with bronchopulmonary dysplasia (BPD) and pulmonary hypertension (PH).

Study design: Retrospective data were obtained from subjects (n=109) attending a BPD clinic. Subjects were stratified by the presence or absence of PH before and after 2 months of age. Analytic methods included t-tests, χ(2) tests and regression.

Result: Subjects with BPD and PH present after 2 months of age were hospitalized for 2.2 months longer than those without PH (P=0.02). These subjects were 4.5 times more likely to receive home supplemental oxygen or mechanical ventilation (P=0.03). No difference in the risk of respiratory morbidities after initial hospital discharge was seen with PH.

Conclusion: PH in preterm infants is associated with longer initial hospitalizations and a higher likelihood of requiring home respiratory support. This has implications for counseling families and reducing the medical, psychosocial, and economic burden of BPD and PH.

MeSH terms

  • Bronchopulmonary Dysplasia / complications
  • Bronchopulmonary Dysplasia / therapy*
  • Female
  • Gastrostomy
  • Home Care Services, Hospital-Based / statistics & numerical data*
  • Humans
  • Hypertension, Pulmonary / complications
  • Hypertension, Pulmonary / therapy*
  • Infant, Premature
  • Infant, Premature, Diseases / therapy*
  • Length of Stay / statistics & numerical data*
  • Logistic Models
  • Male
  • Respiration, Artificial
  • Retrospective Studies