Objective: To evaluate the efficacy and safety of brachytherapy plus operation for salivary gland malignant tumors.
Methods: From June 2006 to June 2011, a total of 105 patients with salivary gland malignant tumors undergone brachytherapy by implantation of iodine 125 seeds. The effectiveness was evaluated by periodical radiological film and computed tomography. The complications were analyzed.
Results: Among them, 92 patients were observed for 12 - 60 months. The rates of clinical response rate (CRPR) and no change (NC) were 91.3% (84/92) and 8.7% (8/92) respectively of the patients. Pain, mucosa ulcer, skin darkness and radiation osteomyelitis were common complications.
Conclusion: The combined regimen of operation and brachytherapy of iodine 125 seed implantation for salivary gland malignant tumors is quite effective and convenient. And it has fewer complications.