Acute promyelocytic leukemia with insertion of PML exon 7c: a novel variant transcript related to good prognosis that is not detected with real-time polymerase chain reaction

Leuk Lymphoma. 2013 Oct;54(10):2294-6. doi: 10.3109/10428194.2013.767457. Epub 2013 Feb 16.
No abstract available

Publication types

  • Case Reports
  • Letter
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alternative Splicing
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Base Sequence
  • Bone Marrow / pathology
  • Exons*
  • Humans
  • Leukemia, Promyelocytic, Acute / diagnosis
  • Leukemia, Promyelocytic, Acute / drug therapy
  • Leukemia, Promyelocytic, Acute / genetics*
  • Male
  • Middle Aged
  • Molecular Sequence Data
  • Mutagenesis, Insertional*
  • Nuclear Proteins / genetics*
  • Oncogene Proteins, Fusion / genetics
  • Prognosis
  • Promyelocytic Leukemia Protein
  • Real-Time Polymerase Chain Reaction
  • Remission Induction
  • Transcription Factors / genetics*
  • Treatment Outcome
  • Tumor Suppressor Proteins / genetics*

Substances

  • Nuclear Proteins
  • Oncogene Proteins, Fusion
  • Promyelocytic Leukemia Protein
  • Transcription Factors
  • Tumor Suppressor Proteins
  • promyelocytic leukemia-retinoic acid receptor alpha fusion oncoprotein
  • PML protein, human