"One-pot" fabrication of clickable monoliths for enzyme reactors

Chem Commun (Camb). 2013 Feb 18;49(14):1407-9. doi: 10.1039/c2cc37974k.

Abstract

A simple, novel "one-pot" approach was developed for the preparation of organic-silica hybrid monoliths. Two clickable monoliths functionalized with either azido or alkynyl moieties were prepared. The clickable monoliths were further used for the fabrication of enzyme reactors via "click chemistry".

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkynes / chemistry
  • Azides / chemistry
  • Catalysis
  • Click Chemistry*
  • Copper / chemistry
  • Enzymes / metabolism*
  • Horseradish Peroxidase / metabolism
  • Kinetics
  • Pepsin A / metabolism
  • Silicon Dioxide / chemistry*

Substances

  • Alkynes
  • Azides
  • Enzymes
  • Silicon Dioxide
  • Copper
  • Horseradish Peroxidase
  • Pepsin A