Abstract
We have described a patient in opioid substitution treatment using heroin to treat her premenstrual complaints. After a short review of the diagnosis and etiology of premenstrual syndrome or premenstrual dysphoric disorder, the relation between premenstrual syndrome/premenstrual dysphoric disorder and opioid receptors is discussed. In the case of the patient described, increasing the dose of methadone in the premenstrual period produced significant clinical improvement.
MeSH terms
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Adult
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Affective Symptoms* / diagnosis
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Affective Symptoms* / drug therapy
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Affective Symptoms* / etiology
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Affective Symptoms* / physiopathology
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Dose-Response Relationship, Drug
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Female
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Heroin Dependence / drug therapy*
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Humans
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Irritable Mood / drug effects
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Irritable Mood / physiology
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Methadone / administration & dosage*
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Opiate Substitution Treatment / methods*
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Premenstrual Syndrome* / complications
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Premenstrual Syndrome* / diagnosis
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Premenstrual Syndrome* / drug therapy
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Premenstrual Syndrome* / physiopathology
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Premenstrual Syndrome* / psychology
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Substance Abuse Detection
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Treatment Outcome