Metastatic basal cell carcinoma: report of a case and review of the literature

Stephanie Moser; Jan Borm; Daniela Mihic-Probst; Christine Jacobsen; Astrid L Kruse Gujer

doi:10.1016/j.oooo.2012.04.030

Metastatic basal cell carcinoma: report of a case and review of the literature

Oral Surg Oral Med Oral Pathol Oral Radiol. 2014 Feb;117(2):e79-82. doi: 10.1016/j.oooo.2012.04.030. Epub 2013 Jan 10.

Authors

Stephanie Moser¹, Jan Borm², Daniela Mihic-Probst³, Christine Jacobsen⁴, Astrid L Kruse Gujer⁴

Affiliations

¹ Department of Craniomexillofacial and Oral Surgery, University Hospital Zurich. Electronic address: stephanie.moser@zzm.uzh.ch.
² Department of Craniomexillofacial and Oral Surgery, University Hospital Zurich.
³ Institute of Surgical Pathology, University of Zurich.
⁴ Department of Craniomaxillofacial Surgery, University Hospital Zurich.

PMID: 23313228
DOI: 10.1016/j.oooo.2012.04.030

Abstract

Background: Metastatic basal cell carcinoma (MBCC) is defined as primary cutaneous basal cell carcinoma (BCC) that spreads to distant sites as histologically similar metastatic deposits of BCC. BCCs are semimalignant, destructive, and invasive. Metastases are very rare, with an incidence of 0.0028%-0.5%.

Case report: A female patient with Gorlin-Goltz syndrome and a rare case of a basal cell carcinoma with an additional regional lymph node metastasis is presented.

Conclusions: This case highlights the importance of a multidisciplinary approach to and frequent monitoring of patients with Gorlin-Goltz syndrome. Early diagnosis and surgical treatment are still the treatment of first choice.

Publication types

Case Reports
Review

MeSH terms

Basal Cell Nevus Syndrome / pathology*
Basal Cell Nevus Syndrome / surgery
Female
Head and Neck Neoplasms / pathology*
Head and Neck Neoplasms / surgery
Humans
Lymph Node Excision
Lymphatic Metastasis / pathology*
Middle Aged