Long-term outcome of self expandable metal stents for biliary obstruction in chronic pancreatitis

JOP. 2013 Jan 10;14(1):57-62. doi: 10.6092/1590-8577/870.

Abstract

Context: Insertion of a self-expandable metal stent is still controversial for treatment of benign common bile duct stenosis but can be a valuable alternative to surgical treatment.

Objective: Aim of our study was to analyze the efficacy of covered and uncovered self-expandable metal stent in patients with chronic pancreatitis and common bile duct stenosis.

Material and methods: Twenty patients with common bile duct stenosis due to alcoholic chronic pancreatitis were retrospective analyzed. All patients had advanced chronic pancreatitis, presenting with calcifications in pancreatic head. Uncovered self-expandable metal stent (uSEMS) were used in 11 patients (3 females, 8 males) while in 9 patients (3 females, 6 males) partially covered self-expandable metal stent (cSEMS) were inserted. All patients treated with self-expandable metal stent had contraindications for surgery.

Results: Overall mean follow up time was 155 weeks: 206 (52-412) weeks in uSEMS, and 93 (25-233) weeks in cSEMS, respectively. Stent patency was in mean 118 weeks: 159 (44-412) weeks in uSEMS and 67 (25-150) weeks in cSEMS (P=0.019). In the uSEMS group, reintervention was necessary in 5 patients (45%) due to stent obstruction, whereas in the cSEMS group 4 patients (44%) needed reintervention (2 obstructions, 2 migration). Stent migration is an early complication, compared to obstruction (P<0.05), and in cSEMS obstruction occurred significantly earlier compared to uSEMS (P<0.05).

Conclusion: Patency of uSEMS was significantly longer compared to partially cSEMS. Available self-expandable metal stent, unfortunately, do not meet the demands on successful treatment of benign common bile duct stenosis.

MeSH terms

  • Adult
  • Aged
  • Biliary Tract Diseases / etiology
  • Biliary Tract Diseases / surgery*
  • Common Bile Duct / pathology
  • Common Bile Duct / surgery*
  • Constriction, Pathologic / etiology
  • Constriction, Pathologic / surgery
  • Female
  • Follow-Up Studies
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Middle Aged
  • Pancreatitis, Alcoholic / complications
  • Pancreatitis, Chronic / complications*
  • Retrospective Studies
  • Stents*
  • Time Factors
  • Treatment Outcome