Mycobacterium smegmatis in skin biopsy specimens from patients with suppurative granulomatous inflammation

J Clin Microbiol. 2013 Mar;51(3):1028-30. doi: 10.1128/JCM.03421-12. Epub 2013 Jan 9.

Abstract

Formalin-fixed, paraffin-embedded skin biopsy specimens, including 72 suppurative granulomatous inflammation (SGI) and 47 non-SGI controls, were tested for mycobacteria by using a broad-range PCR and a suspension array identification system. Mycobacterium smegmatis was detected in 13 (18.1%) of the SGI skin biopsy specimens, which was significantly more than 2 (4.3%) in the controls (odds ratio, 5.73; 95% confidence interval, 1.21 to 27.06; P = 0.028).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Biopsy
  • Child
  • Child, Preschool
  • Female
  • Granulomatous Disease, Chronic / epidemiology
  • Granulomatous Disease, Chronic / microbiology
  • Humans
  • Male
  • Mycobacterium Infections, Nontuberculous / epidemiology
  • Mycobacterium Infections, Nontuberculous / microbiology*
  • Mycobacterium smegmatis / isolation & purification*
  • Prevalence
  • Skin / microbiology*
  • Skin Diseases, Bacterial / epidemiology
  • Skin Diseases, Bacterial / microbiology*
  • Young Adult