Treatment of cystic craniopharyngioma with 90Y-Colloid. Four clinical cases

Rev Esp Med Nucl Imagen Mol. 2013 Sep-Oct;32(5):321-3. doi: 10.1016/j.remn.2012.11.003. Epub 2013 Jan 3.
[Article in English, Spanish]

Abstract

Craniopharyngioma is a histologically benign and frequently cystic intracranial tumor. It may present aggressive behavior due to compression from nearby structures. Its therapeutic management is complicated because although surgery is the usual treatment of choice, it is not exempt of high morbidity and mortality and frequent tumor recurrence. In craniopharyngiomas with a significant cystic component,internal irradiation with radioactive isotopes is a therapeutic alternative to conventional treatments. We present the cases of four patients with cystic craniopharyngiomas who were treated with intracystic administration of 90Y-colloid, and their evolution after the treatment.

Keywords: Craneofaringioma quístico; Cystic craniopharyngioma; Guided radiotherapy; Intracavitary irradiation; Irradiación intracavitaria; Itrio-90 coloide; Radioterapia guiada; Yttrium-90 colloid.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Colloids / administration & dosage
  • Combined Modality Therapy
  • Craniopharyngioma / complications
  • Craniopharyngioma / radiotherapy*
  • Craniopharyngioma / surgery
  • Craniotomy
  • Cysts / radiotherapy*
  • Diplopia / etiology
  • Female
  • Humans
  • Hypopituitarism / etiology
  • Injections, Intralesional
  • Male
  • Middle Aged
  • Paresis / etiology
  • Pituitary Neoplasms / complications
  • Pituitary Neoplasms / radiotherapy*
  • Pituitary Neoplasms / surgery
  • Radiopharmaceuticals / administration & dosage
  • Radiopharmaceuticals / therapeutic use*
  • Remission Induction
  • Vision Disorders / etiology
  • Young Adult
  • Yttrium Radioisotopes / administration & dosage
  • Yttrium Radioisotopes / therapeutic use*

Substances

  • Colloids
  • Radiopharmaceuticals
  • Yttrium Radioisotopes

Supplementary concepts

  • Combined Pituitary Hormone Deficiency