The article presents data on features of uneasiness and depression in elderly and senile patients with arterial hypertension. Age and gender differences of these problems are discussed. The patients of the senior age groups have normal level of uneasiness on a scale of situational uneasiness, and women of advanced age and patients of control group have the raised level of uneasiness on a scale of personal uneasiness. The gender differences on a scale of personal uneasiness are revealed. Frustrations of a depressive range are noted at assessment of the depressive status in all age and gender groups.