Objective: To explore information about label use and off label use about Kudeizi injection in clinical practice.
Method: Three Chinese literature databases were searched and 237 articles were downloaded. Efficacy evaluation information about the study question was extracted by researchers in the Excel form. Finally, 3 systematic reviews and 190 RCTs, 20 clinical controlled trials, 21 case series and 3 case reports were identified. It only did an overview on three systematic reviews and 190 RCTs.
Result: It is found that the most common disease treated by Kudiezi injection were cerebral infarction, coronary heart disease and angina pectoris. There are also many off label use about Kudiezi injection.
Conclusion: Although there are more or less quality problems for these clinical trials of Kudiezi injection, researchers have already made effort to improve trials. There will be still a long way to develop good clinical trials for Kudiezi injection.