Hospital centralized monitoring is an important method to adverse drug reaction (ADR) of traditional Chinese medicine (TCM) injection. Nowadays, our hospital centralized monitoring to TCM injection is difficult to carry out normally, because of little attention that the medical staffs pay to, poor professional knowledge of researchers, unsound reporting system, unreasonable organization structures of ADR and so on. We hope to establish a quality control system of hospital centralized monitoring to TCM injection, by means of emphasizing the importance of ADR monitoring to TCM injection, establishing and perfecting the management mechanism, strengthening staff member training, building the four-steps inspecting rule, implementing barcode monitoring, to strengthen safety supervision of TCM injection, guarantee medication safety.