Computed tomography in an 81-year-old woman revealed obstruction of the inferior vena cava by a large primary vascular leiomyosarcoma, and involvement of the right renal vein. She underwent successful en-bloc resection of the tumor, right kidney, hepatic segments IV and VI, and inferior vena cava, without caval reconstruction. A renal vein-to-remaining infrahepatic inferior vena cava saphenous vein graft bypass was performed for left renal venous drainage. The need for vascular reconstruction is not always mandatory.