The effect of increased maximum power output on perioperative and early postoperative outcome in photoselective vaporization of the prostate

Lasers Surg Med. 2013 Jan;45(1):28-33. doi: 10.1002/lsm.22108. Epub 2012 Dec 31.

Abstract

Background and objective: Preclinical studies suggest an increased vaporization rate and speed of the 532 nm 180-W XPS GreenLight laser (180-W) compared with the 120-W HPS GreenLight laser (120-W) and the 80-W PV GreenLight laser (80-W). To test the clinical relevance of this observation we analyzed intraoperative data and early postoperative results after photoselective vaporization of the prostate (PVP) with the 180-W, 120-W, and 80-W laser.

Study design/materials and methods: A retrospective pair-to-pair comparison was performed including 80 consecutive patients who underwent PVP for the treatment of benign prostate enlargement with the 180-W, 120-W, and 80-W laser. The groups matched concerning age, prostate volume, PSA-value, and preoperative catheterization. Primary study outcome measurement was PSA-value reduction at 3 months; intraoperative data, perioperative complications, and early postoperative functional course were secondary study outcome measurements.

Results: Energy application per case (kJ), preoperative prostate volume (kJ/ml) operating time (kJ/minute), and lasing time (kJ/minute) was significantly higher with the 180-W laser. Prevalence of impaired visibility due to bleeding was comparable between the 180-W and the 120-W laser but significantly lower with 80-W. Duration of hospitalization was shorter with the 180-W laser compared to the former laser systems. During the postoperative course of 3 months voiding parameters and micturition symptoms significantly improved in all groups, the incidence of postoperative dysuria was comparable. Postoperative PSA-value reduction was significantly higher after treatment with the 180-W laser.

Conclusions: With the 180-W laser, higher energy application and higher speed of tissue vaporization leads to increased tissue vaporization compared to the former 120-W and 80-W laser systems. Clinical efficacy and perioperative safety are maintained with the higher powered laser.

Publication types

  • Comparative Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Hospitalization
  • Humans
  • Lasers, Solid-State / therapeutic use*
  • Low-Level Light Therapy / adverse effects
  • Low-Level Light Therapy / instrumentation*
  • Male
  • Prostatic Hyperplasia / complications
  • Prostatic Hyperplasia / pathology
  • Prostatic Hyperplasia / therapy*
  • Recovery of Function
  • Retrospective Studies
  • Time Factors
  • Transurethral Resection of Prostate / adverse effects
  • Transurethral Resection of Prostate / instrumentation*
  • Treatment Outcome