Brentuximab vedotin combined with donor lymphocyte infusions for early relapse of Hodgkin lymphoma after allogeneic stem-cell transplantation induces tumor-specific immunity and sustained clinical remission

J Clin Oncol. 2013 Feb 10;31(5):e59-63. doi: 10.1200/JCO.2012.43.6832. Epub 2012 Dec 26.
No abstract available

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Antineoplastic Agents / administration & dosage
  • Antineoplastic Agents / adverse effects
  • Antineoplastic Agents / therapeutic use*
  • Apoptosis / immunology*
  • Brentuximab Vedotin
  • CD4-Positive T-Lymphocytes / immunology
  • Combined Modality Therapy
  • Drug Administration Schedule
  • Graft vs Host Disease / etiology
  • HLA-A2 Antigen / immunology
  • Hematopoietic Stem Cell Transplantation* / adverse effects
  • Hodgkin Disease / drug therapy
  • Hodgkin Disease / immunology*
  • Hodgkin Disease / surgery
  • Hodgkin Disease / therapy*
  • Humans
  • Immunoconjugates / administration & dosage
  • Immunoconjugates / adverse effects
  • Immunoconjugates / therapeutic use*
  • Immunotherapy, Adoptive* / methods
  • Ki-1 Antigen / antagonists & inhibitors*
  • Lymphocytes / immunology*
  • NK Cell Lectin-Like Receptor Subfamily B / immunology
  • Polyneuropathies / chemically induced
  • Recurrence
  • Remission Induction
  • Shock, Septic / etiology
  • T-Lymphocytes / immunology*
  • T-Lymphocytes, Cytotoxic / immunology
  • Th17 Cells / immunology
  • Thrombocytopenia / chemically induced
  • Transplantation, Homologous
  • Treatment Outcome

Substances

  • Antineoplastic Agents
  • HLA-A2 Antigen
  • Immunoconjugates
  • KLRB1 protein, human
  • Ki-1 Antigen
  • NK Cell Lectin-Like Receptor Subfamily B
  • Brentuximab Vedotin