Are there race-dependent endothelial cell responses to exercise?

Exerc Sport Sci Rev. 2013 Jan;41(1):44-54. doi: 10.1097/JES.0b013e318279cbbd.

Abstract

African Americans have an endothelial dysfunction that likely contributes to their high prevalence of hypertension. Endothelial cell (EC) responses to stimuli could play a role in the development of endothelial dysfunction and hypertension. High physiological levels of vascular laminar shear stress can alter EC phenotype profoundly. It is not known whether there are race-dependent EC responses to laminar shear stress.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Biomarkers / metabolism
  • Black or African American*
  • Endothelial Cells / metabolism
  • Endothelial Cells / physiology*
  • Exercise / physiology*
  • Health Status Disparities*
  • Humans
  • Inflammation / ethnology
  • Inflammation / metabolism
  • Inflammation / physiopathology
  • Nitric Oxide / metabolism
  • Nitric Oxide Synthase / metabolism
  • Oxidative Stress / physiology
  • Stress, Physiological / physiology
  • Vascular Diseases / ethnology*
  • Vascular Diseases / metabolism
  • Vascular Diseases / physiopathology
  • White People*

Substances

  • Biomarkers
  • Nitric Oxide
  • Nitric Oxide Synthase