Abstract
African Americans have an endothelial dysfunction that likely contributes to their high prevalence of hypertension. Endothelial cell (EC) responses to stimuli could play a role in the development of endothelial dysfunction and hypertension. High physiological levels of vascular laminar shear stress can alter EC phenotype profoundly. It is not known whether there are race-dependent EC responses to laminar shear stress.
Publication types
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Research Support, N.I.H., Extramural
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Review
MeSH terms
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Biomarkers / metabolism
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Black or African American*
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Endothelial Cells / metabolism
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Endothelial Cells / physiology*
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Exercise / physiology*
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Health Status Disparities*
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Humans
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Inflammation / ethnology
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Inflammation / metabolism
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Inflammation / physiopathology
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Nitric Oxide / metabolism
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Nitric Oxide Synthase / metabolism
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Oxidative Stress / physiology
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Stress, Physiological / physiology
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Vascular Diseases / ethnology*
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Vascular Diseases / metabolism
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Vascular Diseases / physiopathology
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White People*
Substances
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Biomarkers
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Nitric Oxide
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Nitric Oxide Synthase