A common structure for the potexviruses

Virology. 2013 Feb 5;436(1):173-8. doi: 10.1016/j.virol.2012.11.008. Epub 2012 Dec 11.

Abstract

We have used fiber diffraction, cryo-electron microscopy, and scanning transmission electron microscopy to confirm the symmetry of three potexviruses, potato virus X, papaya mosaic virus, and narcissus mosaic virus, and to determine their low-resolution structures. All three viruses have slightly less than nine subunits per turn of the viral helix. Our data strongly support the view that all potexviruses have approximately the same symmetry. The structures are dominated by a large domain at high radius in the virion, with a smaller domain, which includes the putative RNA-binding site, extending to low radius.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Amino Acid Sequence
  • Binding Sites
  • Capsid / chemistry*
  • Capsid / ultrastructure*
  • Capsid Proteins / chemistry*
  • Cryoelectron Microscopy
  • Microscopy, Electron, Scanning Transmission
  • Potexvirus / chemistry
  • Potexvirus / classification
  • Potexvirus / ultrastructure*
  • Protein Structure, Secondary
  • RNA, Viral / chemistry
  • X-Ray Diffraction

Substances

  • Capsid Proteins
  • RNA, Viral