Sliding to the rescue of damaged DNA

Elife. 2012 Dec 13:1:e00347. doi: 10.7554/eLife.00347.

Abstract

Single-molecule imaging experiments have shed new light on the methods used by the enzyme RecA to align single- and double-stranded DNA so that double-strand breaks can be repaired.

Keywords: DNA repair; E. coli; FRET; Homologous Recombination; Single Molecule.

Publication types

  • Comment

MeSH terms

  • DNA, Single-Stranded / chemistry*
  • Escherichia coli / genetics*
  • Escherichia coli Proteins / chemistry*
  • Homologous Recombination*
  • Rec A Recombinases / chemistry*

Substances

  • DNA, Single-Stranded
  • Escherichia coli Proteins
  • Rec A Recombinases