[Clinical utility of measurement of procalcitonin for diagnosis of urosepsis]

Hinyokika Kiyo. 2012 Oct;58(10):539-42.
[Article in Japanese]

Abstract

We assessed the diagnostic value of procalcitonin (PCT) in urosepsis on 54 patients with urinary tract infections (UTI), suspected of having urosepsis. The results of urine culture, blood culture, and serum concentrations of PCT were analyzed. Overall, the sensitivity and specificity of PCT for bacteremia were as follows : 100 and 31.6% at concentrations of >0.5 ng/ml and 75.0 and 78.9% at concentrations of >10 ng/ml. we concluded that the PCT level could be a reliable early marker suggestive of urosepsis, and may be helpful when deciding whether to perform immediate urological intervention or not.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Biomarkers / blood
  • Calcitonin / blood*
  • Calcitonin Gene-Related Peptide
  • Female
  • Humans
  • Male
  • Middle Aged
  • Protein Precursors / blood*
  • Sensitivity and Specificity
  • Sepsis / diagnosis*
  • Sepsis / etiology
  • Urinary Tract Infections / complications
  • Urinary Tract Infections / diagnosis*

Substances

  • Biomarkers
  • CALCA protein, human
  • Protein Precursors
  • Calcitonin
  • Calcitonin Gene-Related Peptide