Flavodonfuran: a new difuranylmethane derivative from the mangrove endophytic fungus Flavodon flavus PSU-MA201

Nat Prod Res. 2013;27(19):1722-6. doi: 10.1080/14786419.2012.750315. Epub 2012 Dec 13.

Abstract

One new difuranylmethane derivative, flavodonfuran (1), together with tremulenolide A (2) was isolated from the mangrove-derived fungus Flavodon flavus PSU-MA201.The difuranylmethane derivative based on 1 is rare in natural products. Their structures were established by spectroscopic evidence. Compound 2 exhibited mild antibacterial and antifungal activities against Staphylococcus aureus ATCC25923 and Cryptococcus neoformans ATCC90113, respectively.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry*
  • Anti-Bacterial Agents / pharmacology
  • Antifungal Agents / chemistry*
  • Antifungal Agents / pharmacology
  • Basidiomycota / chemistry*
  • Cryptococcus neoformans / drug effects
  • Furans / chemistry*
  • Furans / pharmacology
  • Microbial Sensitivity Tests
  • Molecular Structure
  • Staphylococcus aureus / drug effects

Substances

  • Anti-Bacterial Agents
  • Antifungal Agents
  • Furans
  • furan