Abstract
A kinetic method has been developed for highly sensitive and selective detection of pyrophosphate anions (PPi) by using a fluorophore labelled single-stranded-DNA-Al(III) complex system. The facile and spectrum-tunable fluorescent sensor enables rapid detection of PPi in urine and cell lysate solutions without the need for complex pre-cleanup procedures.
Publication types
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Evaluation Study
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Research Support, Non-U.S. Gov't
MeSH terms
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Aluminum / chemistry
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Anions / analysis*
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Anions / urine
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Cell Line
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Coordination Complexes / chemistry
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DNA, Single-Stranded / chemistry*
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Diphosphates / analysis*
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Diphosphates / urine
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Fluorescent Dyes / chemistry*
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Humans
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Kinetics
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Sensitivity and Specificity
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Spectrometry, Fluorescence / methods
Substances
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Anions
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Coordination Complexes
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DNA, Single-Stranded
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Diphosphates
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Fluorescent Dyes
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diphosphoric acid
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Aluminum