Neuroenhancement of the aging brain: restoring skill acquisition in old subjects

Ann Neurol. 2013 Jan;73(1):10-5. doi: 10.1002/ana.23761. Epub 2012 Dec 7.

Abstract

Objective: Decline in cognitive functions, including impaired acquisition of novel skills, is a feature of older age that impacts activities of daily living, independence, and integration in modern societies.

Methods: We tested whether the acquisition of a complex motor skill can be enhanced in old subjects by the application of transcranial direct current stimulation (tDCS) to the motor cortex.

Results: The main finding was that old participants experienced substantial improvements when training was applied concurrent with tDCS, with effects lasting for at least 24 hours.

Interpretation: These results suggest noninvasive brain stimulation as a promising and safe tool to potentially assist functional independence of aged individuals in daily life.

Publication types

  • Controlled Clinical Trial
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Aging / physiology*
  • Aging / psychology
  • Attention / physiology
  • Brain / physiology
  • Cross-Over Studies
  • Double-Blind Method
  • Female
  • Humans
  • Male
  • Middle Aged
  • Motor Cortex / physiology*
  • Motor Skills / physiology*
  • Pilot Projects
  • Psychomotor Performance / physiology*
  • Transcranial Magnetic Stimulation* / methods
  • Young Adult