Postprocedural neuropathy after atrial fibrillation ablation

J Interv Card Electrophysiol. 2013 Apr;36(3):279-85. doi: 10.1007/s10840-012-9724-z. Epub 2012 Dec 9.

Abstract

Purpose: Access-related neuropathy after atrial fibrillation (AF) ablation is underappreciated. We intend to describe the incidence, management, and prognosis of postprocedural neuropathy after AF ablation.

Methods: We performed a retrospective analysis of all consecutive patients with postprocedural neuropathy who underwent AF ablation in three high-volume tertiary care hospitals between January 2007 and April 2011.

Results: Of the 3,128 patients who underwent AF ablation during the study period, 25 (0.8 %) patients had postprocedural neuropathy and were included in the current study. Mean age was 58.5 ± 11.5 years with 18 (72 %) being males and 14 (56 %) having paroxysmal AF. Ulnar nerve, lateral femoral cutaneous nerve manifesting as meralgia paresthetica, and femoral nerve were involved in 5 (20 %), 13 (54 %), and 7 (26 %) of the patients, respectively. Majority of neuropathies were associated with periprocedural hematomas (19, 76 %), and a quarter (19/72, 26 %) of all hematomas were associated with neuropathy. Initial treatment included warm and cold compresses followed by nonsteroidal anti-inflammatory and narcotic pain medications. In addition to the above regimen, in some patients (11, 44 %), oral gabapentin was used and it was associated with a shorter time to symptom resolution (9.4 vs. 14.1 days, p = 0.007). All patients were symptom free within 90 days of the procedure.

Conclusion: Postprocedural neuropathy after AF ablation is rare and is frequently associated with a periprocedural hematoma. Patients typically become symptom free within 90 days of the procedure, and gabapentin may have a role in earlier symptom resolution.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Atrial Fibrillation / epidemiology*
  • Atrial Fibrillation / surgery*
  • Catheter Ablation / statistics & numerical data*
  • Causality
  • Comorbidity
  • Female
  • Humans
  • Incidence
  • Kansas / epidemiology
  • Male
  • Middle Aged
  • Peripheral Nerve Injuries / epidemiology*
  • Peripheral Nervous System Diseases / epidemiology*
  • Postoperative Complications / epidemiology*
  • Retrospective Studies
  • Risk Factors