Carrier molecules for use in veterinary vaccines

Vaccine. 2013 Jan 11;31(4):596-602. doi: 10.1016/j.vaccine.2012.11.067. Epub 2012 Dec 7.

Abstract

The practice of immunization of animals and humans has been carried out for centuries and is generally accepted as the most cost effective and sustainable method of infectious disease control. Over the past 20 years there have been significant changes in our ability to produce antigens by conventional extraction and purification, recombinant DNA and synthesis. However, many of these products need to be combined with carrier molecules to generate optimal immune responses. This review covers selected topics in the development of carrier technologies for use in the veterinary vaccine field, including glycoconjugate and peptide vaccines, microparticle and nanoparticle formulations, and finally virus-like particles.

Publication types

  • Review

MeSH terms

  • Animals
  • Glycoconjugates / immunology*
  • Glycoconjugates / therapeutic use
  • Nanoparticles / chemistry*
  • Vaccination / veterinary*
  • Vaccines / chemistry
  • Vaccines / immunology*
  • Vaccines, Conjugate / immunology
  • Vaccines, Subunit / immunology*
  • Vaccines, Virus-Like Particle / immunology*

Substances

  • Glycoconjugates
  • Vaccines
  • Vaccines, Conjugate
  • Vaccines, Subunit
  • Vaccines, Virus-Like Particle