Tower microneedle via reverse drawing lithography for innocuous intravitreal drug delivery

Adv Healthc Mater. 2013 Jun;2(6):812-6. doi: 10.1002/adhm.201200239. Epub 2012 Dec 3.

Abstract

The "tower microneedle" (TM) via reverse drawing lithography for intravitreal injection by fabricating a long hollow microneedle on the blunt hypodermic needle: The hollow hole between the microneedle and hypodermic needle is aligned concentrically, and fifteen degree bevel angle is introduced to TM by laser cutting to achieve intravitreal injection with minimal damage to eye tissue.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Equipment Design
  • Equipment Failure Analysis
  • Intravitreal Injections / instrumentation*
  • Microinjections / instrumentation*
  • Miniaturization
  • Molecular Imprinting / instrumentation*
  • Needles*
  • Photography / instrumentation*
  • Rabbits