Age-associated changes in muscle activity during isometric contraction

Abstract

Introduction: We investigated the effect of age on the complexity of muscle activity and the variance in the force of isometric contraction.

Methods: Surface electromyography (sEMG) from biceps brachii muscle and force of contraction were recorded from 96 subjects (20-70 years of age) during isometric contractions.

Results: There was a reduction in the complexity of sEMG associated with aging. The relationship of age and complexity was approximated using a bilinear fit, with the average knee point at 45 years. There was an age-associated increase in the coefficient of variation (CoV) of the force of muscle contraction, and this increase was correlated with the decrease in complexity of sEMG (r(2) = 0.76).

Conclusions: There was an age-associated increase in CoV and also a reduction in the complexity of sEMG. The correlation between these 2 factors can be explained based on the age-associated increase in motor unit density.