[Bacteriology of community-acquired peritonitis in children treated in the university hospital of Marrakech]

Ann Fr Anesth Reanim. 2013 Jan;32(1):60-2. doi: 10.1016/j.annfar.2012.10.031. Epub 2012 Nov 27.
[Article in French]

Abstract

Introduction: The available microbiological data on community-acquired peritonitis in children are inadequate, and antibiotic therapy is not consensual. Our work aims to study the bacteriology of peritonitis in children in our region and discuss the appropriate antibiotherapy.

Patients and methods: A descriptive study spread over one year. We collected cases of peritonitis in which a microbiological study of peritoneal fluid was performed.

Results: Of 38 cases, the most frequently isolated bacteria is Escherichia coli (E. coli) (50%). Its sensitivity was 64% to amoxicillin-clavulanate, 93.33% to third generation cephalosporins (C3G) and 100% to ertapenem and aminozides.

Conclusion: We find a high rate of resistance of E. coli to amoxicillin-clavulanic acid. This prompts us to reconsider our therapeutic approach. We believe that the association C3G+aminoglycoside+metronidazole should be used first-line in the pediatric peritonitis in our context.

Publication types

  • English Abstract

MeSH terms

  • Adolescent
  • Anti-Bacterial Agents / pharmacology
  • Anti-Bacterial Agents / therapeutic use
  • Ascitic Fluid / microbiology
  • Cephalosporins / therapeutic use
  • Child
  • Child, Preschool
  • Community-Acquired Infections / drug therapy
  • Community-Acquired Infections / epidemiology
  • Community-Acquired Infections / microbiology*
  • Escherichia coli Infections / drug therapy
  • Escherichia coli Infections / microbiology
  • Female
  • Hospitals, University
  • Humans
  • Infant
  • Male
  • Metronidazole / therapeutic use
  • Microbial Sensitivity Tests
  • Morocco / epidemiology
  • Peritonitis / drug therapy
  • Peritonitis / epidemiology
  • Peritonitis / microbiology*

Substances

  • Anti-Bacterial Agents
  • Cephalosporins
  • Metronidazole