Abstract
We present a microfluidic platform for the synthesis of monodisperse chitosan based nanoparticles via self-assembly at physiological pH. The resultant nanoparticles are shown to encapsulate hydrophobic anticancer drugs while providing a sustainable release profile with high tunability.
Publication types
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Research Support, Non-U.S. Gov't
MeSH terms
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Antineoplastic Agents, Phytogenic / chemistry
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Chitosan / chemistry*
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Drug Carriers / chemical synthesis
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Drug Carriers / chemistry*
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Hydrogen-Ion Concentration
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Hydrophobic and Hydrophilic Interactions
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Microfluidic Analytical Techniques / instrumentation
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Microfluidic Analytical Techniques / methods*
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Nanoparticles / chemistry*
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Paclitaxel / chemistry
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Particle Size
Substances
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Antineoplastic Agents, Phytogenic
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Drug Carriers
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Chitosan
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Paclitaxel