Smart interface materials integrated with microfluidics for on-demand local capture and release of cells

Adv Healthc Mater. 2012 Sep;1(5):661-8. doi: 10.1002/adhm.201200009. Epub 2012 Jul 9.

Abstract

Stimuli responsive, smart interface materials are integrated with microfluidic technologies creating new functions for a broad range of biological and clinical applications by controlling the material and cell interactions. Local capture and on-demand local release of cells are demonstrated with spatial and temporal control in a microfluidic system.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Acrylic Resins / chemistry*
  • Cell Adhesion
  • Cell Movement
  • Cell Separation / instrumentation*
  • Cells, Cultured
  • Equipment Design
  • Equipment Failure Analysis
  • Flow Cytometry / instrumentation*
  • Heating / instrumentation*
  • Humans
  • Lymphocytes / cytology*
  • Microfluidic Analytical Techniques / instrumentation*
  • Systems Integration

Substances

  • Acrylic Resins
  • poly-N-isopropylacrylamide