Cooperative, nanoparticle-enabled thermal therapy of breast cancer

Adv Healthc Mater. 2012 Jan 11;1(1):84-9. doi: 10.1002/adhm.201100005. Epub 2011 Nov 29.

Abstract

Hollow gold nanoshells are more efficient in heat generation triggered by near infrared laser when they are loaded into porous silicon particles, which results in effective cancer-cell killing in vitro and in vivo. Collective electromagnetic coupling of nanoconfined hollow gold nanoshells leads to dramatic enhancement of thermal ablation.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Cell Line, Tumor
  • Hyperthermia, Induced / methods*
  • Mice
  • Nanoparticles / chemistry*
  • Nanoparticles / therapeutic use*
  • Nanoparticles / ultrastructure
  • Neoplasms, Experimental / pathology*
  • Neoplasms, Experimental / therapy*
  • Particle Size
  • Treatment Outcome