Effect of magnetic field on the ultrafiltration of bovine serum albumin

Bioprocess Biosyst Eng. 2013 Aug;36(8):1087-93. doi: 10.1007/s00449-012-0862-6. Epub 2012 Nov 27.

Abstract

This work evaluates the effects of a static magnetic field on the permeation of bovine serum albumin (BSA) in a tangential ultrafiltration membrane module. Experimental tests were carried out at different pHs using a poly(sulfone) membrane with molecular weight cut off of 60 kDa under the influence of a 0.4 T neodymium-iron-boron magnetic field. Results showed an increase in the permeate flux of water after the cleaning procedures of the new and reused membranes in the presence of the magnetic field. The elusive mechanism of magnetic memory is also shown to take place for the water fluxes fully recovered after the cleaning procedures when the magnetic field was applied to the system before the permeation. When the magnetic field was applied during permeation, the water fluxes presented lower percent of recuperation after the cleaning procedures, thus suggesting that the BSA solution may have somewhat been influenced by magnetic memory.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Boron / chemistry
  • Cattle
  • Equipment Design
  • Hydrogen-Ion Concentration
  • Iron / chemistry
  • Magnetic Fields*
  • Membranes, Artificial
  • Neodymium / chemistry
  • Polymers / chemistry
  • Serum Albumin, Bovine / chemistry*
  • Serum Albumin, Bovine / isolation & purification
  • Solutions
  • Sulfones / chemistry
  • Temperature
  • Ultrafiltration / instrumentation*
  • Ultrafiltration / methods*

Substances

  • Membranes, Artificial
  • Polymers
  • Solutions
  • Sulfones
  • polysulfone P 1700
  • Serum Albumin, Bovine
  • Neodymium
  • Iron
  • Boron