Abstract
There is a need for a new approach to managing women with primary ovarian insufficiency. This condition is a serious chronic disease that may have far reaching effects on physical and emotional health. An integrative and collaborative approach to management works best. To maintain wellness, most women with primary ovarian insufficiency need to reassess their primary source of meaning and purpose in life and how this diagnosis may have threatened that part of who they are. They also need assessment with regard to bone health, thyroid and adrenal function, determination of FMR1 premutation and karyotype status, and ongoing estradiol-progestin hormone replacement.
Published by Elsevier Inc.
Publication types
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Research Support, N.I.H., Extramural
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Adult
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Counseling
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Estradiol / administration & dosage
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Estrogen Replacement Therapy* / methods
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Female
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Fragile X Mental Retardation Protein / genetics*
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Humans
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Menopause, Premature / genetics*
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Menopause, Premature / psychology
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Mutation
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Polymorphism, Single Nucleotide
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Pregnancy
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Primary Ovarian Insufficiency / diagnosis*
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Primary Ovarian Insufficiency / drug therapy
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Primary Ovarian Insufficiency / genetics*
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Primary Ovarian Insufficiency / psychology
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Progestins / administration & dosage
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Prognosis
Substances
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FMR1 protein, human
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Progestins
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Fragile X Mental Retardation Protein
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Estradiol