In France, only one case of tick-borne human granulocytic anaplasmosis has been described in the literature (in 2003). Here, we report 5 new human cases of Anaplasma phagocytophilum infection from north-eastern France diagnosed in our laboratory in south-eastern France by serology and molecular biology. This increase is directly related to more physician interest in this disease and the implementation of a new PCR tool.
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