Abstract
Background:
Cidofovir is an antiviral agent which inhibits the DNA polymerase of different viruses. Its use has been described for papillomavirus infections.
Methods:
Descriptive retrospective study, including patients with difficult to treat anogenital warts who were treated with cidofovir cream.
Results:
Nine immunocompetent patients were treated, where 6 of them had a complete response and 3 of them a partial response.
Conclusion:
Cidofovir cream could be a useful therapeutic alternative, although further studies are required to establish the best dosage and its cost-effectiveness.
Copyright © 2012 Elsevier España, S.L. All rights reserved.
MeSH terms
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Administration, Topical
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Adult
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Aminoquinolines / therapeutic use
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Antiviral Agents / administration & dosage
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Antiviral Agents / therapeutic use*
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Anus Diseases / drug therapy*
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Anus Diseases / surgery
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Child
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Cidofovir
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Combined Modality Therapy
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Condylomata Acuminata / drug therapy*
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Condylomata Acuminata / surgery
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Cryotherapy
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Cytosine / administration & dosage
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Cytosine / analogs & derivatives*
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Cytosine / therapeutic use
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Disease Susceptibility
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Drug Evaluation
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Drug Resistance, Viral
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Electrocoagulation
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Female
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Genital Diseases, Female / drug therapy
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Genital Diseases, Female / surgery
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Genital Diseases, Male / drug therapy*
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Genital Diseases, Male / surgery
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Humans
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Imiquimod
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Immunocompetence
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Male
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Organophosphonates / administration & dosage
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Organophosphonates / therapeutic use*
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Podophyllotoxin / therapeutic use
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Remission Induction
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Retrospective Studies
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Young Adult
Substances
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Aminoquinolines
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Antiviral Agents
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Organophosphonates
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Cytosine
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Cidofovir
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Podophyllotoxin
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Imiquimod