[Treatment of anogenital warts with topical cidofovir]

Enferm Infecc Microbiol Clin. 2013 Apr;31(4):222-6. doi: 10.1016/j.eimc.2012.09.015. Epub 2012 Nov 20.
[Article in Spanish]

Abstract

Background: Cidofovir is an antiviral agent which inhibits the DNA polymerase of different viruses. Its use has been described for papillomavirus infections.

Methods: Descriptive retrospective study, including patients with difficult to treat anogenital warts who were treated with cidofovir cream.

Results: Nine immunocompetent patients were treated, where 6 of them had a complete response and 3 of them a partial response.

Conclusion: Cidofovir cream could be a useful therapeutic alternative, although further studies are required to establish the best dosage and its cost-effectiveness.

Publication types

  • Review

MeSH terms

  • Administration, Topical
  • Adult
  • Aminoquinolines / therapeutic use
  • Antiviral Agents / administration & dosage
  • Antiviral Agents / therapeutic use*
  • Anus Diseases / drug therapy*
  • Anus Diseases / surgery
  • Child
  • Cidofovir
  • Combined Modality Therapy
  • Condylomata Acuminata / drug therapy*
  • Condylomata Acuminata / surgery
  • Cryotherapy
  • Cytosine / administration & dosage
  • Cytosine / analogs & derivatives*
  • Cytosine / therapeutic use
  • Disease Susceptibility
  • Drug Evaluation
  • Drug Resistance, Viral
  • Electrocoagulation
  • Female
  • Genital Diseases, Female / drug therapy
  • Genital Diseases, Female / surgery
  • Genital Diseases, Male / drug therapy*
  • Genital Diseases, Male / surgery
  • Humans
  • Imiquimod
  • Immunocompetence
  • Male
  • Organophosphonates / administration & dosage
  • Organophosphonates / therapeutic use*
  • Podophyllotoxin / therapeutic use
  • Remission Induction
  • Retrospective Studies
  • Young Adult

Substances

  • Aminoquinolines
  • Antiviral Agents
  • Organophosphonates
  • Cytosine
  • Cidofovir
  • Podophyllotoxin
  • Imiquimod