Membrane dynamics during cytokinesis

Curr Opin Cell Biol. 2013 Feb;25(1):92-8. doi: 10.1016/j.ceb.2012.10.012. Epub 2012 Nov 21.

Abstract

Endocytic membrane transport has recently emerged as a key process required for the successful completion of cytokinesis. Specific endocytic membranes act in concert with the cytoskeleton and ESCRT proteins to regulate the various stages of cytokinesis. In this review, we focus on the different endocytic Arf and Rab GTPases and their interaction proteins that regulate organelle transport to the intracellular bridge during cytokinesis. The identity and function of these endocytic organelles during the late stages of cell division will also be discussed.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Actins / metabolism
  • Animals
  • Biological Transport / physiology
  • Cell Membrane / metabolism*
  • Cytokinesis*
  • Cytoskeleton / metabolism
  • Endosomal Sorting Complexes Required for Transport
  • Endosomes / metabolism
  • Humans
  • Membrane Fusion
  • rab GTP-Binding Proteins / metabolism

Substances

  • Actins
  • Endosomal Sorting Complexes Required for Transport
  • rab GTP-Binding Proteins