Spiroheterocyclization of methyl 1-aryl-3-cinnamoyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates by the action of 3-(arylamino)-1H-inden-1-ones

Pavel S Silaichev; Valeriy O Filimonov; Pavel A Slepukhin; Andrey N Maslivets

doi:10.3390/molecules171213787

Spiroheterocyclization of methyl 1-aryl-3-cinnamoyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates by the action of 3-(arylamino)-1H-inden-1-ones

Molecules. 2012 Nov 22;17(12):13787-94. doi: 10.3390/molecules171213787.

Authors

Pavel S Silaichev¹, Valeriy O Filimonov, Pavel A Slepukhin, Andrey N Maslivets

Affiliation

¹ Department of Organic Chemistry, Perm State National Research University, Perm 614066, Russia. silaychev@yahoo.com

Abstract

Methyl 1-aryl-3-cinnamoyl-4,5-dioxo-4,5-dihydro-1H-pyrrole-2-carboxylates interact with 3-(arylamino)-1H-inden-1-ones to give the corresponding 1,1'-diaryl-3'-cinnamoyl-4'-hydroxy-1H-spiro[indeno[1,2-b]pyrrole-3,2'-pyrrole]-2,4,5'(1'H)-triones in good yields.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Cinnamates / chemistry*
Indenes / chemistry*
Molecular Structure
Proline / analogs & derivatives*
Proline / chemical synthesis
Proline / chemistry
Pyrroles* / chemical synthesis
Pyrroles* / chemistry
Structure-Activity Relationship*

Substances

Cinnamates
Indenes
Pyrroles
2-pyrrolecarboxylic acid
Proline