Dopamine: on the threshold of sleep

Curr Biol. 2012 Nov 20;22(22):R949-51. doi: 10.1016/j.cub.2012.09.007.

Abstract

A new study examining the neural circuitry regulating sleep in Drosophila has identified a pair of dopamine neurons that signal to the fan-shaped body to suppress sleep. These neurons are separate from the dopamine neurons that regulate motivation, memory, and feeding, suggesting that independent populations of dopamine neurons regulate distinct behaviors.

MeSH terms

  • Animals
  • Behavior, Animal / physiology
  • Dopamine / metabolism*
  • Drosophila / physiology*
  • Neurons / metabolism*
  • Receptors, Dopamine / physiology*
  • Sleep / physiology*

Substances

  • Receptors, Dopamine
  • Dopamine