A highly sensitive gold nanoparticle-based colorimetric probe for pyrophosphate using a competition assay approach

Chem Commun (Camb). 2013 Jan 7;49(2):152-4. doi: 10.1039/c2cc37379c. Epub 2012 Nov 20.

Abstract

In this study, a mixture of [Zn(2)(1,3-bis[bis(2-pyridylmethyl)aminomethyl]benzene)](4+) ([Zn(2)(BBPAB)](4+)) and 11-mercaptoundecylphosphoric acid functionalized gold nanoparticles (Phos-AuNPs) is shown to be a highly sensitive colorimetric probe that can easily detect pyrophosphate (PPi) at less than 200 nM with the naked eye.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Colorimetry
  • Coordination Complexes / chemistry
  • Diphosphates / analysis
  • Gold / chemistry*
  • Metal Nanoparticles / chemistry*
  • Zinc / chemistry

Substances

  • Coordination Complexes
  • Diphosphates
  • Gold
  • Zinc